BDBM172943 US9096579, 45

SMILES CN1CCN(C2CCN(C(=O)c3cc4cc(Nc5nccc(-c6cn(C)cn6)n5)cc(Cl)c4[nH]3)CC2)C1=O

InChI Key InChIKey=HPHJILIKBNYMGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172943   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 172943BDBM172943(US9096579, 45)
Affinity DataIC50: 0.800nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent