BDBM17364 1,2,4-Triazole Compound, 22::5-{[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}-N-(2-methylphenyl)-4H-1,2,4-triazol-3-amine

SMILES Cc1cc(CSc2nnc(Nc3ccccc3C)[nH]2)no1

InChI Key InChIKey=QWFBFFLKHCOYBC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17364   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17364(1,2,4-Triazole Compound, 22 | 5-{[(5-methyl-1,2-ox...)
Affinity DataKi:  3.60nM ΔG°:  -11.4kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed