BDBM174158 US9688669, Example 26

SMILES Cc1ccn(CC#Cc2cncc(c2)[C@H]2NC(=O)O[C@@H]2c2cccc(F)c2)n1

InChI Key InChIKey=RKTYNEVDTQOZGQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174158   

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM174158(US9688669, Example 26)
Affinity DataEC50:  46nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent