BDBM175382 1,3-Dimethyl-8-[3-{2-(morpholin-1-yl)-2-oxoethoxy}-phenyl]xanthine (14f, RB-375)

SMILES Cn1c(=O)c2[nH]c(-c3cccc(OCC(=O)N4CCOCC4)c3)nc2n(C)c1=O

InChI Key InChIKey=GGUBALWRKUTXNZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175382   

TargetAdenosine receptor A2a(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175382BDBM175382(1,3-Dimethyl-8-[3-{2-(morpholin-1-yl)-2-oxoethoxy}...)
Affinity DataKi:  679nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175382BDBM175382(1,3-Dimethyl-8-[3-{2-(morpholin-1-yl)-2-oxoethoxy}...)
Affinity DataKi:  5.37E+3nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A3 [I248L](Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175382BDBM175382(1,3-Dimethyl-8-[3-{2-(morpholin-1-yl)-2-oxoethoxy}...)
Affinity DataKi:  7.90E+3nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175382BDBM175382(1,3-Dimethyl-8-[3-{2-(morpholin-1-yl)-2-oxoethoxy}...)
Affinity DataKi: >1.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed