BDBM175387 8-[{4-(2-(Diethylaminoethylamino)-2-oxoethoxy)-3-methoxy}-phenyl]-1,3-dimethyl-xanthine (15b, RB-388)

SMILES CCN(CC)CCNC(=O)COc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1OC

InChI Key InChIKey=POHMJKWKQLDWJH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175387   

TargetAdenosine receptor A2a(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175387BDBM175387(8-[{4-(2-(Diethylaminoethylamino)-2-oxoethoxy)-3-m...)
Affinity DataKi:  692nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175387BDBM175387(8-[{4-(2-(Diethylaminoethylamino)-2-oxoethoxy)-3-m...)
Affinity DataKi: >1.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175387BDBM175387(8-[{4-(2-(Diethylaminoethylamino)-2-oxoethoxy)-3-m...)
Affinity DataKi: >1.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A3 [I248L](Human)
Panjab University

LigandChemical structure of BindingDB Monomer ID 175387BDBM175387(8-[{4-(2-(Diethylaminoethylamino)-2-oxoethoxy)-3-m...)
Affinity DataKi: >3.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed