BDBM176597 US9120761, 11
SMILES CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(OC(F)(F)F)c1
InChI Key InChIKey=QSOOWIITUXDNSS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 176597
Affinity DataIC50: 2.20nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2) S...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMpH: 7.4Assay Description:In running buffer (0.01 M HEPES pH 7.4, 0.15 M NaCl, 0.005% Surfactant P20, mM MgCl2, and 1% DMSO)N-terminally GST-fused purified FAK enzyme was capt...More data for this Ligand-Target Pair
TargetIsoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298](Homo sapiens (Human))
Cancer Therapeutics Crc
US Patent
Cancer Therapeutics Crc
US Patent
Affinity DataIC50: 5.98E+4nMpH: 7.4Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair