BDBM176597 US9120761, 11

SMILES CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(OC(F)(F)F)c1

InChI Key InChIKey=QSOOWIITUXDNSS-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 176597   

TargetFocal adhesion kinase 1(Mus musculus (Mouse))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM176597(US9120761, 11)
Affinity DataIC50:  2.20nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2) S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Mus musculus (Mouse))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM176597(US9120761, 11)
Affinity DataKd:  1.70nMpH: 7.4Assay Description:In running buffer (0.01 M HEPES pH 7.4, 0.15 M NaCl, 0.005% Surfactant P20, mM MgCl2, and 1% DMSO)N-terminally GST-fused purified FAK enzyme was capt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298](Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM176597(US9120761, 11)
Affinity DataIC50:  5.98E+4nMpH: 7.4Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
In DepthDetails US Patent