BDBM17667 2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)methyl]-4-methoxy-1H-1,3-benzodiazole::CHEMBL292923::benzimidazole analogue, 44
SMILES COc1cccc2n(Cc3c(F)cccc3F)c(nc12)-c1c(F)cccc1F
InChI Key InChIKey=YEFVOKDOLXVJEU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 17667
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Nci-Fcrdc
Nci-Fcrdc
Affinity DataIC50: 7.30nMpH: 8.0 T: 37°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair