BDBM17787 benzimidazole-urea, 15::methyl N-(6-{4-[(phenylcarbamoyl)amino]phenoxy}-1H-1,3-benzodiazol-2-yl)carbamate

SMILES COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)cc2[nH]1

InChI Key InChIKey=LSYSLIJSKJGOJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17787   

LigandPNGBDBM17787(benzimidazole-urea, 15 | methyl N-(6-{4-[(phenylca...)
Affinity DataIC50:  32nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17787(benzimidazole-urea, 15 | methyl N-(6-{4-[(phenylca...)
Affinity DataIC50:  3.20E+3nMpH: 7.4 T: 22°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed