BDBM17793 benzimidazole-urea, 21::methyl N-[6-(4-{[(3-chlorophenyl)carbamoyl]amino}phenoxy)-1H-1,3-benzodiazol-2-yl]carbamate

SMILES COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cc2[nH]1

InChI Key InChIKey=XOMNBLZPGBTSHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17793   

LigandPNGBDBM17793(benzimidazole-urea, 21 | methyl N-[6-(4-{[(3-chlor...)
Affinity DataIC50:  6.30nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17793(benzimidazole-urea, 21 | methyl N-[6-(4-{[(3-chlor...)
Affinity DataIC50:  40nMpH: 7.4 T: 22°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed