BDBM178001 (E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-en-1-one (1)::US11866416, Compound 2

SMILES Oc1cccc(\C=C\C(=O)c2ccccc2O)c1

InChI Key InChIKey=BLEVPIDFNNFTHJ-CMDGGOBGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 178001   

TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara

LigandPNGBDBM178001((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...)
Affinity DataIC50:  4.47E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM178001((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...)
Affinity DataIC50:  6.40E+4nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM178001((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM178001((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...)
Affinity DataIC50:  9.18E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed