BDBM17804 5-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-2-({2-[(methoxycarbonyl)amino]-1H-1,3-benzodiazol-6-yl}oxy)-1-oxidopyridin-1-ium::N-(5-(5-((2-Fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)-1-oxo-2-pyridyloxy)-1H-benzimidazol-2-yl)-carbamate::benzimidazole-urea, 32

SMILES COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)c[n+]3[O-])cc2[nH]1

InChI Key InChIKey=XAIJULJJMLLWOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17804   

TargetAngiopoietin-1 receptor(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 17804BDBM17804(N-(5-(5-((2-Fluoro-5-(trifluoromethyl)phenyl)amino...)
Affinity DataIC50: 71nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17804BDBM17804(N-(5-(5-((2-Fluoro-5-(trifluoromethyl)phenyl)amino...)
Affinity DataIC50: 230nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed