BDBM178079 1-(3-Chlorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)pyridin-2(1H)-one (35h)

SMILES COc1cc2nccc(Oc3ccc(cc3F)-c3cccn(-c4cccc(Cl)c4)c3=O)c2cc1OC

InChI Key InChIKey=PVGIMGZYLRFRTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178079   

TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science & Technology

LigandPNGBDBM178079(1-(3-Chlorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-...)
Affinity DataIC50: 3nMpH: 7.4Assay Description:The substrate of poly (Glu, Tyr) 4:1 (20 lg/mL) (Sigma, St. Louis, MO, USA) was precoated in 96-well ELISA plates, and the kinase was incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed