BDBM17818 1-{4-[(2-amino-1H-1,3-benzodiazol-6-yl)oxy]phenyl}-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea::benzimidazole-urea, 45

SMILES Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2[nH]1

InChI Key InChIKey=GKOMRRDSXJXWIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17818   

LigandPNGBDBM17818(1-{4-[(2-amino-1H-1,3-benzodiazol-6-yl)oxy]phenyl}...)
Affinity DataIC50: 15nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17818(1-{4-[(2-amino-1H-1,3-benzodiazol-6-yl)oxy]phenyl}...)
Affinity DataIC50: 60nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed