BDBM17820 N-(6-(4-((2-Fluoro-5(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)-2-(1H-pyrrol-1-yl)benzamide::N-{6-[4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1H-1,3-benzodiazol-2-yl}-2-(1H-pyrrol-1-yl)benzamide::benzimidazole-urea, 48

SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ccc3nc(NC(=O)c4ccccc4-n4cccc4)[nH]c3c2)cc1)C(F)(F)F

InChI Key InChIKey=IKNROBNGBWFAHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17820   

LigandPNGBDBM17820(N-(6-(4-((2-Fluoro-5(trifluoromethyl)phenyl)aminoc...)
Affinity DataIC50: 510nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17820(N-(6-(4-((2-Fluoro-5(trifluoromethyl)phenyl)aminoc...)
Affinity DataIC50: 1.30E+3nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed