BDBM17835 2-(2,6-dimethylphenoxy)-N-[(2S,4S,5S)-5-{[(5S)-3-(3-acetylphenyl)-2-oxo-1,3-oxazolidin-5-yl]formamido}-4-hydroxy-1,6-diphenylhexan-2-yl]acetamide::Hydroxyethylene Isostere-Based Compound, 16e
SMILES CC(=O)c1cccc(c1)N1C[C@H](OC1=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@H](Cc1ccccc1)NC(=O)COc1c(C)cccc1C
InChI Key InChIKey=UVTHAOVACKMIFO-ZYXDSXQBSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 17835
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 35.1nM ΔG°: -10.3kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair