BDBM178938 US9126931, 104

SMILES CC1(C)c2cc(N3CCC(N4CCC(F)(F)CC4)CC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21

InChI Key InChIKey=AFHMLHTVDDTUBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178938   

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 178938BDBM178938(US9126931, 104)
Affinity DataIC50: 1.68nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent