BDBM179026 US9126931, 543

SMILES CC(C)(C)N1CCN(c2cc3c(cc2Br)C(=O)c2c([nH]c4cc(C#N)ccc24)C32CCOCC2)CC1

InChI Key InChIKey=APVIDLUCFAXGHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179026   

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 179026BDBM179026(US9126931, 543)
Affinity DataIC50: 0.320nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent