BDBM17948 (2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({[2-(3-methoxypropoxy)phenyl]formamido}methyl)-2,8-dimethylnonanamide::Renin nonpeptide inhibitor, 8

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)C[C@H](CNC(=O)c1ccccc1OCCCOC)C(C)C

InChI Key InChIKey=JYPXLSXKONMTFW-HTDNTCHWSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17948   

TargetPepsin A(Pig)
Novartis Pharmaceuticals

LigandPNGBDBM17948((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({[2-(3-...)
Affinity DataIC50: >1.00E+5nMpH: 2.0 T: 37°CAssay Description:In vitro potencies of compounds against purified porcine pepsin were determined by its cleavage of substrate hemoglobin. After incubation, proteins w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM17948((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({[2-(3-...)
Affinity DataIC50:  0.900nMpH: 7.2 T: 37°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)