BDBM179539 US9126978, 1

SMILES CN1c2ccc(Cl)cc2C(=O)N[C@H](CC2CC=C(C=C2)c2ccncc2)C1=O

InChI Key InChIKey=MHDJVMRMWAXJRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179539   

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM179539(US9126978, 1)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM179539(US9126978, 1)
Affinity DataIC50: 3.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent