BDBM179541 US9126978, 3

SMILES CN1C2=CCCC(Cl)=C2C(=O)N[C@H](Cc2ccc(cc2)-c2ccncc2)C1=O

InChI Key InChIKey=UNQFLSVFOAWMOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179541   

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM179541(US9126978, 3)
Affinity DataIC50: 860nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM179541(US9126978, 3)
Affinity DataIC50: 3.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent