BDBM179824 US9676701, 60 (Trans)-2-(6-(1H-indazol-6-yl)pyridin-3-yl)cyclopropanamine hydrochloride

SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1ccc2cn[nH]c2c1

InChI Key InChIKey=LPLJGHQCDHYWHH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179824   

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179824(US9676701, 60 (Trans)-2-(6-(1H-indazol-6-yl)pyridi...)
Affinity DataKi:  500nM ΔG°:  -8.59kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179824(US9676701, 60 (Trans)-2-(6-(1H-indazol-6-yl)pyridi...)
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179824(US9676701, 60 (Trans)-2-(6-(1H-indazol-6-yl)pyridi...)
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent