BDBM180217 US9133157, 122::US9133157, 99

SMILES COC(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@H](c1ccc(s1)[C@@H](CO)N(CCC(C)(C)C)S(=O)(=O)c1cn2ccnc2cn1)C(F)(F)F

InChI Key InChIKey=IAZLUHKFRIPGQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 180217   

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180217(US9133157, 99 | US9133157, 122)
Affinity DataIC50: 3.39nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180217(US9133157, 99 | US9133157, 122)
Affinity DataIC50: 5.78nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent