BDBM180236 US9133157, 121

SMILES COC(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@H](c1ccc(s1)[C@@H](CO)N(CCC(C)(C)C)S(=O)(=O)c1cn2ncnc2cn1)C(F)(F)F

InChI Key InChIKey=RSSSNAYKFSNUGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180236   

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180236(US9133157, 121)
Affinity DataIC50: 3.59nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent