BDBM18058 3-[({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine::amidinothiouronium, 13

SMILES NC(=N)NC(=N)SCc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NZYVKNSSAMMYEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18058   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
University of Prince Edward Island

LigandPNGBDBM18058(3-[({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)me...)
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMed