BDBM18062 3-({[(2-hydroxy-5-nitrophenyl)methyl]sulfanyl}methanimidoyl)guanidine::amidinothiouronium, 17

SMILES NC(=N)NC(=N)SCc1cc(ccc1O)[N+]([O-])=O

InChI Key InChIKey=OSBNISOPIWSYMS-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18062   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
University of Prince Edward Island

LigandPNGBDBM18062(3-({[(2-hydroxy-5-nitrophenyl)methyl]sulfanyl}meth...)
Affinity DataIC50: 1.51E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2007
Entry Details Article
PubMed