BDBM180861 US9133180, 2

SMILES Cc1ccc2[nH]ccc2c1-c1nc(C(N)=O)c(o1)-c1ccc(cc1)N1CCNC(C)(C)C1

InChI Key InChIKey=XSLUZOLUJPDNGT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180861   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sareum

US Patent
LigandPNGBDBM180861(US9133180, 2)
Affinity DataIC50: 0.770nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetAurora kinase B(Human)
Sareum

US Patent
LigandPNGBDBM180861(US9133180, 2)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sareum

US Patent
LigandPNGBDBM180861(US9133180, 2)
Affinity DataIC50: 13.6nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent