BDBM180961 US9133187, I-104

SMILES CC(C)Nc1ncc2CCN(Cc2n1)C(=O)NC(CCC#N)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=GOMVFWUINXVVRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180961   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM180961(US9133187, I-104)
Affinity DataIC50:  2.20nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent