BDBM18201 3-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 10h

SMILES CC1CN(CC(F)(F)F)c2cc3c(cc(=O)[nH]c3cc2O1)C(F)(F)F

InChI Key InChIKey=PLVSLGFGXYLLNA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18201   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18201(3-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluorometh...)
Affinity DataKi:  15nM ΔG°:  -11.1kcal/mole EC50:  8.90nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18201(3-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluorometh...)
Affinity DataKi:  7.00E+3nM ΔG°:  -6.53kcal/molepH: 7.4 T: 4°CAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed