BDBM18212 1-(cyclopropylmethyl)-2-ethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 16d

SMILES CCC1COc2cc3[nH]c(=O)cc(c3cc2N1CC1CC1)C(F)(F)F

InChI Key InChIKey=WHDBVRBJWGZQAF-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18212   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18212(1-(cyclopropylmethyl)-2-ethyl-9-(trifluoromethyl)-...)
Affinity DataKi:  23nM EC50:  2.30nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18212(1-(cyclopropylmethyl)-2-ethyl-9-(trifluoromethyl)-...)
Affinity DataKi:  5.40E+3nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed