BDBM182462 US9145392, 163

SMILES CN(C)CCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1-c1cn[nH]c1)-c1ccc(F)c(C)c1

InChI Key InChIKey=NUPWMMJWFAYJED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182462   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Patent

US Patent
LigandPNGBDBM182462(US9145392, 163)
Affinity DataIC50:  4.80nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182462(US9145392, 163)
Affinity DataIC50:  0.730nMpH: 7.5 T: 25°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent