BDBM182483 US9145392, 184

SMILES COc1c(N)ncnc1N1CCC(CC1)c1nc(cn1CC1CNC1)-c1ccc(F)c(C)c1

InChI Key InChIKey=KVMVAUMDSYMRST-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182483   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Patent

US Patent

LigandBDBM182483(US9145392, 184)Copy SMILESCopy InChI

Affinity DataIC50:  2.30nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

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TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent

LigandBDBM182483(US9145392, 184)Copy SMILESCopy InChI

Affinity DataIC50:  0.260nMpH: 7.5 T: 25°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI
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