BDBM182798 US9145414, 161

SMILES N[C@H]1CCCC[C@H]1Nc1nnc(C(N)=O)c(Nc2cc3ccccc3s2)n1

InChI Key InChIKey=HJDDOMBYBZNDRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 182798   

TargetTyrosine-protein kinase SYK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182798(US9145414, 161)
Affinity DataIC50: 0.280nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182798(US9145414, 161)
Affinity DataIC50: 420nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent publicat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182798(US9145414, 161)
Affinity DataIC50: 2.00E+3nMpH: 7.5Assay Description:Conditions for assaying the in vitro inhibitory activity of the compound against KDR kinase activity were set with reference to the statement in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent