BDBM183344 US9150546, I-518::US9688643, I-518::US9718790, I-0527

SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(C[C@H](C)C(O)=O)c(=O)n1Cc1ccc(C)cc1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 183344   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM183344(US9150546, I-518 | US9688643, I-518 | US9718790, I...)
Affinity DataIC50:  7nMpH: 7.5 T: 37°CAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM183344(US9150546, I-518 | US9688643, I-518 | US9718790, I...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at P2X3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM183344(US9150546, I-518 | US9688643, I-518 | US9718790, I...)
Affinity DataIC50:  7nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM183344(US9150546, I-518 | US9688643, I-518 | US9718790, I...)
Affinity DataIC50:  7nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent