BDBM183363 US9150546, I-537::US9688643, I-537::US9718790, I-0546

SMILES CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1

InChI Key InChIKey=GOGSMTUTGMMREV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 183363   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 183363BDBM183363(US9688643, I-537 | US9718790, I-0546 | US9150546, ...)
Affinity DataIC50: 19nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 183363BDBM183363(US9688643, I-537 | US9718790, I-0546 | US9150546, ...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at P2X3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 183363BDBM183363(US9688643, I-537 | US9718790, I-0546 | US9150546, ...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 183363BDBM183363(US9688643, I-537 | US9718790, I-0546 | US9150546, ...)
Affinity DataIC50: 19nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
US Patent