BDBM184598 US9155743, 28

SMILES CCCN1Cc2nc(NC(=O)[C@H](C)NC)ccc2N(C1=O)c1ccccc1

InChI Key InChIKey=CGXRIGREXGFZPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 184598   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM184598(US9155743, 28)
Affinity DataIC50: 505nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, cIAP-1 or cIAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM184598(US9155743, 28)
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, cIAP-1 or cIAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
US Patent