BDBM185096 US9156811, DDD100802

SMILES CN1CCCN(CCCc2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)N(CC(F)F)c2c(C)nn(C)c2C)CC1

InChI Key InChIKey=XISLEJQCQIHTJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185096   

TargetGlycylpeptide N-tetradecanoyltransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Univeristy of Dundee

US Patent
LigandPNGBDBM185096(US9156811, DDD100802)
Affinity DataIC50:  3nMpH: 7.4 T: 25°CAssay Description:Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Univeristy of Dundee

US Patent
LigandPNGBDBM185096(US9156811, DDD100802)
Affinity DataIC50:  5nMpH: 7.4 T: 25°CAssay Description:Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Univeristy of Dundee

US Patent
LigandPNGBDBM185096(US9156811, DDD100802)
Affinity DataIC50:  101nMpH: 7.4 T: 25°CAssay Description:Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...More data for this Ligand-Target Pair
In DepthDetails US Patent