BDBM185355 US9156831, 6

SMILES C[C@H](CO)C(=O)N1CCC(CC1)c1nc(-c2cnc(N)c(n2)-c2nnc(o2)C(C)(C)C)n(C)n1

InChI Key InChIKey=LOLDQPMMGNHKHJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185355   

LigandChemical structure of BindingDB Monomer ID 185355BDBM185355(US9156831, 6)
Affinity DataIC50: 12nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 185355BDBM185355(US9156831, 6)
Affinity DataIC50: 32nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 185355BDBM185355(US9156831, 6)
Affinity DataIC50: 3.42E+3nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent