BDBM185361 US9156831, 1

SMILES Cn1nc(nc1-c1cnc(N)c(n1)-c1nnc(o1)C(C)(C)C)C1CCN(CC1)C(=O)CCO

InChI Key InChIKey=BICOKLIHOJCQPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185361   

LigandChemical structure of BindingDB Monomer ID 185361BDBM185361(US9156831, 1)
Affinity DataIC50: 14nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 185361BDBM185361(US9156831, 1)
Affinity DataIC50: 23nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 185361BDBM185361(US9156831, 1)
Affinity DataIC50: 2.24E+3nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent