BDBM185558 US9156845, 217

SMILES Cn1cc(cc1C#N)-c1c[nH]c2ncnc(N3CCOCC3)c12

InChI Key InChIKey=IYQTYHISVSPMSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 185558   

LigandPNGBDBM185558(US9156845, 217)
Affinity DataIC50: 6.37nMpH: 7.5Assay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandPNGBDBM185558(US9156845, 217)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of GST-tagged human LRRK2 G2019S mutant expressed in Insect cell using ERM as substrate measured after 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM185558(US9156845, 217)
Affinity DataIC50: 13nMpH: 7.5Assay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2016
Entry Details
US Patent

LigandPNGBDBM185558(US9156845, 217)
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged recombinant human LRRK2 expressed in Insect cell using ERM as substrate measured after 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed