BDBM185615 US9156856, 26::US9493431, 26

SMILES Clc1ccc(cc1)-c1ccccc1CN1CCN(CC1)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(\C=C\c2ncon2)s1

InChI Key InChIKey=SPZMXLLBHGMIIA-FYWRMAATSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185615   

LigandPNGBDBM185615(US9156856, 26 | US9493431, 26)
Affinity DataKi:  393nM ΔG°:  -8.73kcal/moleT: 25°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM185615(US9156856, 26 | US9493431, 26)
Affinity DataKi:  393nM ΔG°:  -8.73kcal/moleT: 25°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent