BDBM185618 US9156856, 29::US9493431, 29

SMILES Cc1nn(C)c(Cl)c1S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=ZNDKAGYBLMFUNI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185618   

LigandPNGBDBM185618(US9156856, 29 | US9493431, 29)
Affinity DataKi:  340nM ΔG°:  -8.82kcal/moleT: 25°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM185618(US9156856, 29 | US9493431, 29)
Affinity DataKi:  340nM ΔG°:  -8.82kcal/moleT: 25°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent