BDBM186200 US9163013, 17

SMILES COc1ccc(cn1)-c1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccc(o4)C(O)=O)CC3)c2c1

InChI Key InChIKey=ZOFDKUGNFQINCC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186200   

TargetGlycogen synthase kinase-3 beta(Human)
Angelini

Curated by ChEMBL

LigandBDBM186200(US9163013, 17)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant GSK-3beta using Ulight-CFFKNIVTPRTPPPSQQGK-amide as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetGlycogen synthase kinase-3 beta(Human)
Angelini

Curated by ChEMBL

LigandBDBM186200(US9163013, 17)Copy SMILESCopy InChI

Affinity DataIC50:  20nMT: 22°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI
Copy reaction URL