BDBM186445 US9163021, 103

SMILES CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnccc12

InChI Key InChIKey=NXCHDYUPIAJKRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186445   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186445(US9163021, 103)
Affinity DataIC50:  15.2nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent