BDBM186446 US9163021, 104

SMILES CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cn3nc(cc3C)C(F)(F)F)c2)c2cnccc12

InChI Key InChIKey=DBZREFSEGLLBIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186446   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186446(US9163021, 104)
Affinity DataIC50:  13.8nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In DepthDetails US Patent