BDBM187038 US9169209, Table 3, Compound 71

SMILES CCCOc1ccc(cc1Cl)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1

InChI Key InChIKey=NPMBERQAJIPDHQ-LFYBBSHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187038   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM187038(US9169209, Table 3, Compound 71)
Affinity DataIC50:  5.60nMpH: 7.5 T: 25°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In DepthDetails US Patent