BDBM187137 US9670181, 17 6,7-dimethoxy-1-methyl-4-(naphthalen-2-ylmethyl)isoquinolin-3-ol

SMILES COc1cc2c(C)nc(O)c(Cc3ccc4ccccc4c3)c2cc1OC

InChI Key InChIKey=GZNZXNRRUAJXKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187137   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM187137(US9670181, 17 6,7-dimethoxy-1-methyl-4-(naphthalen...)
Affinity DataIC50:  14nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE® from Perkin Elmer). This c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent