BDBM187308 US9169240, 47

SMILES COc1nc(-c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)c(O)c(=O)[nH]1

InChI Key InChIKey=KTPGVMICGMWNPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187308   

TargetEndothelial lipase(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187308BDBM187308(US9169240, 47)
Affinity DataIC50: 19nMpH: 8.0Assay Description:The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent