BDBM190937 (*R)-4-(((8-cyano-4-oxochroman-7-yl)oxy)(2,6-dimethylpyridin-4-yl)methyl)benzamide::US12516038, Example 110a

SMILES Cc1cc([C@H](Oc2ccc3c(c2C#N)OCCC3=O)c2ccc(C(N)=O)cc2)cc(C)n1

InChI Key InChIKey=DLDJESDSUBMXEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190937   

TargetHLA-DR4 protein(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 190937BDBM190937((*R)-4-(((8-cyano-4-oxochroman-7-yl)oxy)(2,6-dimet...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2026
Entry Details
US Patent