BDBM191001 US10077266, Example 114::US9181249, 114::US9708313, 114

SMILES CO[C@H](C)C(=O)N1Cc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NCC(F)F)nc2CC1C

InChI Key InChIKey=CNIJPVCRGBRADO-YSSOQSIOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191001   

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191001(US10077266, Example 114 | US9181249, 114 | US97083...)
Affinity DataIC50:  0.0185nMT: 37°CAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191001(US10077266, Example 114 | US9181249, 114 | US97083...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191001(US10077266, Example 114 | US9181249, 114 | US97083...)
Affinity DataIC50:  1.85E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent