BDBM191027 (5S)-N-((4- chlorophenyl) (naphthalen-1- yl)methyl)-2- oxooxazolidine-5- carboxamide::US12516046, Example 30

SMILES O=C1NC[C@@H](C(=O)NC(c2ccc(Cl)cc2)c2cccc3ccccc23)O1

InChI Key InChIKey=KJQDMORUFQRXQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 191027   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 191027BDBM191027((5S)-N-((4- chlorophenyl) (naphthalen-1- yl)methyl...)
Affinity DataIC50: 2.40nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent